You can, but only if your doctor says it’s okay. Diamox helps some people acclimatize faster, though at 3,726 meters it’s overkill for most healthy trekkers. Plenty of people summit Rinjani without any medication at all.
If you and your doctor decide Diamox makes sense for you, you’d usually start a day or two before the trek. Side effects are real though, tingling fingers, running to the bathroom constantly, and carbonated drinks tasting weird. Our guides at Lombok-Indonesia.org don’t hand out meds, so you’d need to bring your own supply.
Honestly, the non-drug option works great for most folks. The 3D2N itinerary gives your body extra time to adjust naturally, which achieves the same thing without pills. That extra night at the crater rim before the summit attempt is often all the acclimatization most people need.
Whichever path you choose, Diamox isn’t a replacement for physical fitness, proper hydration, and a sensible pace. It’s an optional aid that some people use successfully and others do just fine without. Never take altitude medication without medical guidance, because underlying conditions like kidney problems or sulfonamide allergies can make Diamox dangerous rather than helpful.

